BPC157+TB500 10mg

BPC157+TB500 10mg

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This combination is commonly studied in laboratory settings for its potential to accelerate wound healing, enhance angiogenesis, modulate inflammatory pathways, and support connective tissue repair in musculoskeletal, cardiac, and neural injury models.
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Product description
Details
Research
Mechanism of Action

BPC-157 + TB-500 is a synergistic research-grade peptide combination:

  • BPC-157: A gastric pentadecapeptide studied for its angiogenic and cytoprotective properties.

  • TB-500 (Thymosin Beta-4 Fragment): A peptide investigated for its role in actin mobilization and tissue repair.

This combination is commonly studied in laboratory settings for its potential to accelerate wound healing, enhance angiogenesis, modulate inflammatory pathways, and support connective tissue repair in musculoskeletal, cardiac, and neural injury models.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose BPC-157 + TB-500

  • Complementary Mechanisms: BPC-157 supports angiogenesis and collagen repair, while TB-500 promotes actin polymerization and cell migration.

  • Wound Healing Research: Evaluated for tendon, ligament, and muscle injury recovery in experimental studies.

  • Anti-Inflammatory Effects: Studied for modulation of systemic and localized inflammatory markers.

  • Regenerative Potential: Explored for cardiac, neural, and gastrointestinal tissue protection in research models.

  • Batch Verified: ≥98% purity for both peptides, confirmed by HPLC and Mass Spectrometry.

Important Note

For laboratory and scientific research only. Not for human consumption, therapeutic, or diagnostic use.

Components BPC-157 (Gastric pentadecapeptide) + TB-500 (Thymosin Beta-4 fragment)
Form Two separate lyophilized peptide powders
CAS Number BPC-157: 137525-51-0 | TB-500: 77591-33-4
Molecular Mass BPC-157: ~1419 Da | TB-500: ~4964 Da
Chemical Formula BPC-157: C₆₂H₉₈N₁₆O₂₂ | TB-500: C₂₁₂H₃₅₀N₅₆O₇₈S
Storage -20 °C (dry powder), -80 °C (after reconstitution)
Intended Use For preclinical and in vitro research only
Shelf Life 24 months (lyophilized)

Research Applications

Musculoskeletal Injury Models

The combination of BPC-157 and TB-500 is studied in tendon, ligament, and skeletal muscle injury models. Research indicates it may support accelerated tissue recovery by enhancing angiogenesis and promoting targeted cellular migration【1】.

Anti-Inflammatory Research

Pre-clinical studies show that this peptide combination can reduce inflammatory cytokines such as TNF-α and IL-6, along with oxidative stress markers, providing a controlled environment for inflammation-related research【2】.

Cardiovascular Repair Studies

TB-500 has been examined for its role in actin polymerization and endothelial cell migration, supporting vascular repair and cardiac tissue recovery in laboratory models【3】.

Neuroprotective & Gastrointestinal Research

BPC-157 has demonstrated potential protective effects in neural tissues and experimental gastrointestinal models, contributing to studies on tissue regeneration and cellular protection【4】.

References

  1. Chang J et al. (2014). BPC-157 and Tendon-to-Bone Healing Acceleration. Bone Joint Res.

    https://www.paulinamedicalclinic.com/wp-content/uploads/2019/11/BPC-157-1.pdf
  2. Gao H et al. (2010). Anti-Inflammatory Effects of TB-500 in Injury Models. J Orthop Res.

    https://onlinelibrary.wiley.com/doi/pdf/10.1002/jor.20956
  3. Smart N et al. (2007). Thymosin Beta-4 and Cardiac Repair. Nature.

    https://www.nature.com/articles/nature05383.pdf
  4. Sikiric P et al. (2010). BPC-157 and Gastrointestinal Protection. Curr Pharm Des.

    https://www.ingentaconnect.com/content/ben/cpd/2011/00000017/00000016/art00012

Mechanism of Action (BPC-157 + TB-500 Research Activity)

1. Angiogenesis Induction

BPC-157 has been studied for its ability to influence VEGF pathways, supporting new microvascular formation in controlled laboratory models【Sikiric 2010】.

2. Actin Dynamics & Cellular Migration

TB-500 promotes actin mobilization and cell migration, processes commonly investigated in tissue repair and experimental wound-healing studies【Smart 2007】.

3. Collagen Organization & Matrix Support

The combination has been researched for its effects on extracellular matrix organization, showing potential improvements in collagen deposition and tensile strength in experimental tissue models【Chang 2014】.

4. Anti-Inflammatory Modulation

Both peptides have been studied for their capacity to reduce inflammatory cytokine expression and limit oxidative stress markers in pre-clinical research【Gao 2010】.

5. Systemic & Local Regenerative Effects

The combination is of interest for research due to complementary mechanisms that may support localized healing and broader tissue recovery pathways.

References

  1. Chang J et al. (2014). BPC-157 and Tendon-to-Bone Healing Acceleration. Bone Joint Res.

    https://www.paulinamedicalclinic.com/wp-content/uploads/2019/11/BPC-157-1.pdf
  2. Gao H et al. (2010). Anti-Inflammatory Effects of TB-500 in Injury Models. J Orthop Res.

    https://onlinelibrary.wiley.com/doi/pdf/10.1002/jor.20956
  3. Smart N et al. (2007). Thymosin Beta-4 and Cardiac Repair. Nature.

    https://www.nature.com/articles/nature05383.pdf
  4. Sikiric P et al. (2010). BPC-157 and Gastrointestinal Protection. Curr Pharm Des.

    https://www.ingentaconnect.com/content/ben/cpd/2011/00000017/00000016/art00012
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