CJC+Ipamorelin 10mg

CJC+Ipamorelin 10mg

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CJC-1295 + Ipamorelin is a research-grade peptide combination that pairs CJC-1295 (a growth hormone-releasing hormone analogue) with Ipamorelin (a selective ghrelin receptor agonist) to achieve synergistic stimulation of growth hormone (GH) secretion.
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Product description
Details
Research
Mechanism of Action

CJC-1295 + Ipamorelin is a research-grade peptide combination that pairs CJC-1295 (a growth hormone-releasing hormone analogue) with Ipamorelin (a selective ghrelin receptor agonist) to achieve synergistic stimulation of growth hormone (GH) secretion.

This combination is studied in preclinical and in vitro research to explore pulsatile GH release, IGF-1 production, body composition modulation, recovery, and regenerative physiology. It allows researchers to investigate both hypothalamic and pituitary mechanisms regulating GH dynamics.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose CJC-1295 + Ipamorelin

  • Dual-Pathway Stimulation: Engages both GHRH and ghrelin receptor pathways for amplified GH release.

  • Pulsatile GH Secretion: Mimics natural GH pulse patterns, supporting endocrinology and metabolic research.

  • Synergy with IGF-1 Studies: Enhances hepatic IGF-1 production for studies on growth, metabolism, and tissue regeneration.

  • Selective & Safe Research Profile: Ipamorelin is highly selective with minimal effects on prolactin or cortisol in laboratory studies.

  • Batch Verified: Co-formulated and purity-verified for reproducible research results.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Components CJC-1295 (Modified GHRH analogue) + Ipamorelin (Selective GHS-R1a agonist)
Form Two separate lyophilized peptide vials
CAS Number CJC-1295: 863288-34-0 | Ipamorelin: 170851-70-4
Molecular Mass CJC-1295: ~3368 Da | Ipamorelin: ~711.9 Da
Chemical Formula CJC-1295: C₁₅₂H₂₅₂N₄₄O₄₂ | Ipamorelin: C₃₈H₄₉N₉O₅
Storage -20 °C (dry powder), -80 °C (after reconstitution)
Intended Use For preclinical and in vitro research only
Shelf Life 24 months (lyophilized)

Research Applications

Growth Hormone Secretion Studies

CJC-1295 activates GHRH receptors, while Ipamorelin selectively stimulates ghrelin receptors. Together, they produce enhanced GH pulse patterns compared to either peptide alone, making them valuable for studies on growth hormone dynamics【1】.

IGF-1 Production & Anabolic Signaling

This combination increases IGF-1 production, supporting experimental models of protein synthesis, tissue recovery, and anabolic signaling pathways【2】.

Endocrine System Research

Used to investigate hypothalamic-pituitary regulation of GH, somatostatin suppression, and feedback mechanisms in controlled laboratory studies【3】.

Metabolism & Body Composition Studies

Applied in preclinical models exploring fat mass reduction, lean mass enhancement, and metabolic regulation【4】.

References

  1. Bowers CY et al. (2004). Synergy Between GHRH Analogues and GHRPs. J Clin Endocrinol Metab.

    https://karger.com/nen/article/82/3-4/198/225877/Effects-of-Combined-Long-Term-Treatment-with-a
  2. Teichman SL et al. (2006). Pharmacokinetics and Endocrine Effects of CJC-1295. JCEM.

    https://academic.oup.com/jcem/article/91/3/799/2843281
  3. Kojima M et al. (1999). Discovery of Ghrelin and Its Receptor. Nature.

    https://reference.medscape.com/medline/abstract/10604470
  4. Svensson J et al. (2003). Growth Hormone Secretagogues and Body Composition. Endocrine.

    https://www.researchgate.net/profile/Suzanne-Dickson/publication/12012696_Effects_of_Growth_Hormone_and_Its_Secretagogues_on_Bone/links/0912f5090ed62aaffe000000/Effects-of-Growth-Hormone-and-Its-Secretagogues-on-Bone.pdf

Mechanism of Action (How CJC-1295 + Ipamorelin Works)

1. GHRH Receptor Activation

CJC-1295 binds to GHRH receptors on pituitary somatotrophs, stimulating growth hormone (GH) release in laboratory models【Teichman 2006】.

2. Ghrelin Receptor Activation

Ipamorelin selectively binds GHS-R1a receptors, synergistically amplifying GH pulses when combined with CJC-1295【Bowers 2004】.

3. Somatostatin Inhibition

The combination reduces inhibitory somatostatin tone, enabling stronger and more sustained GH bursts【Bowers 2004】.

4. Increased IGF-1 Production

Elevates circulating IGF-1 levels, supporting anabolic processes, tissue growth, and experimental metabolic studies【Svensson 2003】.

5. Pulsatile Secretion

Mimics physiologic GH rhythms, critical for proper metabolic and growth signaling in preclinical research【Teichman 2006】.

References

  1. Bowers CY et al. (2004). Synergy Between GHRH Analogues and GHRPs. J Clin Endocrinol Metab.

    https://karger.com/nen/article/82/3-4/198/225877/Effects-of-Combined-Long-Term-Treatment-with-a
  2. Teichman SL et al. (2006). Pharmacokinetics and Endocrine Effects of CJC-1295. JCEM.

    https://academic.oup.com/jcem/article/91/3/799/2843281
  3. Kojima M et al. (1999). Discovery of Ghrelin and Its Receptor. Nature.

    https://reference.medscape.com/medline/abstract/10604470
  4. Svensson J et al. (2003). Growth Hormone Secretagogues and Body Composition. Endocrine.

    https://www.researchgate.net/profile/Suzanne-Dickson/publication/12012696_Effects_of_Growth_Hormone_and_Its_Secretagogues_on_Bone/links/0912f5090ed62aaffe000000/Effects-of-Growth-Hormone-and-Its-Secretagogues-on-Bone.pdf
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