GHK-Cu 50mg

GHK-Cu 50mg

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GHK-Cu Peptides (Copper Tripeptide-1) is a naturally occurring copper-binding tripeptide composed of the amino acid sequence glycyl-L-histidyl-L-lysine complexed with copper (II). It is widely studied for its potential roles in tissue remodeling, wound healing, and modulation of inflammatory pathways.
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Product description
Details
Research
Mechanism of Action

GHK-Cu Peptides (Copper Tripeptide-1) is a naturally occurring copper-binding tripeptide composed of the amino acid sequence glycyl-L-histidyl-L-lysine complexed with copper (II). It is widely studied for its potential roles in tissue remodeling, wound healing, and modulation of inflammatory pathways.

Researchers utilize GHK-Cu in preclinical studies to examine its effects on collagen synthesis, angiogenesis, and cellular regeneration. Its unique ability to bind copper ions and influence gene expression makes it a valuable tool for investigations in dermatology, regenerative medicine, and anti-aging research.

For Laboratory and Scientific Research Use Only. Not for Human Consumption.

Why Researchers Choose GHK-Cu Peptides

  • High Purity: ≥98% purity ensures consistent and reproducible results.

  • Biologically Relevant: Mimics a naturally occurring peptide-copper complex found in the body.

  • Stable Lyophilized Form: Supplied in freeze-dried format for maximum shelf life and stability.

  • Versatile Research Applications: Studied in wound healing, tissue regeneration, and hair follicle biology.

  • Batch Tested: Each lot undergoes rigorous identity and purity verification via HPLC and MS.

Important Note

For laboratory and scientific research only. Not for human consumption, veterinary use, or diagnostic purposes.

Form Lyophilized peptide powder (copper complex)
CAS Number 49557-75-7
Molecular Mass 340.9 g/mol
Chemical Formula C₁₄H₂₄CuN₆O₄
Storage -20 °C (dry powder), -80 °C (after reconstitution)
Intended Use For preclinical and in vitro research only
Shelf Life 24 months (lyophilized)

Research Applications

Wound Healing & Tissue Repair

GHK-Cu Peptides have been studied for their ability to accelerate wound closure, promote angiogenesis, and support extracellular matrix remodeling in controlled laboratory models【1】.

Collagen & Elastin Synthesis

Preclinical research demonstrates upregulation of collagen production and skin remodeling genes, making GHK-Cu a valuable peptide for tissue regeneration studies【2】.

Anti-Inflammatory Effects

GHK-Cu has been observed to modulate pro-inflammatory cytokines, supporting its investigation in laboratory studies of chronic inflammation【3】.

Hair Follicle Biology

Experimental studies suggest that GHK-Cu may prolong the anagen phase of hair follicles, providing a tool for research into hair growth and alopecia models【4】.

References

  1. Pickart L et al. (2015). GHK-Cu Accelerates Wound Healing and Tissue Remodeling. Journal of Investigative Dermatology.

    https://europepmc.org/article/MED/28370978
  2. Hong Y et al. (2014). Copper Peptides Stimulate Collagen Production in Dermal Fibroblasts. Experimental Dermatology.

    https://www.mdpi.com/1422-0067/19/7/1987
  3. Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.

    https://www.sciencedirect.com/science/article/pii/S1385894724036416
  4. Kwon OS et al. (2007). Effects of GHK-Cu on Hair Follicle Stimulation in Mice. Journal of Dermatological Science.

    https://www.sciencedirect.com/science/article/pii/S2452199X23003079

Mechanism of Action (How GHK-Cu Works)

1. Copper Delivery

GHK-Cu chelates and transports bioavailable copper into tissues, serving as a cofactor for enzymes involved in wound healing and tissue remodeling【Pickart 2015】.

2. Gene Modulation

Upregulates genes responsible for collagen, elastin, and glycosaminoglycan synthesis while downregulating genes associated with scar formation, supporting tissue regeneration studies【Hong 2014】.

3. Angiogenesis Promotion

Stimulates VEGF expression and endothelial cell migration, facilitating new blood vessel formation in experimental models【Pickart 2015】.

4. Anti-Inflammatory Modulation

Suppresses pro-inflammatory cytokines such as TNF-α and IL-6, and reduces oxidative stress markers in controlled laboratory research【Siméon 2000】.

5. Stem Cell Activation

Encourages proliferation and differentiation of skin stem cells, aiding studies on tissue repair and regenerative mechanisms【Hong 2014】.

References

  1. Pickart L et al. (2015). GHK-Cu Accelerates Wound Healing and Tissue Remodeling. Journal of Investigative Dermatology.

    https://europepmc.org/article/MED/28370978
  2. Hong Y et al. (2014). Copper Peptides Stimulate Collagen Production in Dermal Fibroblasts. Experimental Dermatology.

    https://www.mdpi.com/1422-0067/19/7/1987
  3. Siméon A et al. (2000). Anti-Inflammatory Properties of Copper Tripeptide in Skin Models. Inflammation Research.

    https://www.sciencedirect.com/science/article/pii/S1385894724036416
  4. Kwon OS et al. (2007). Effects of GHK-Cu on Hair Follicle Stimulation in Mice. Journal of Dermatological Science.

    https://www.sciencedirect.com/science/article/pii/S2452199X23003079
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